The gut microbiota have a known role in modulating gut immune homeostasis. Largely, through the development and function of host immune cells, including T helper cells expressing interleukin-17A. It ...

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant ...

With smart DMPK strategies, cross-domain collaboration, and strong CDMO support, companies are pushing past the challenges of ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a ...

Bile acids are essential to digestion, by acting like a kind of detergent that breaks up fat molecules. Fat doesn't dissolve in water, but our digestive system is full of water, so the fat we consume ...

Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

Please provide your email address to receive an email when new articles are posted on . About one-third of celiac patients with persistent diarrhea, despite a gluten-free diet, could also have bile ...