Major depression (MD) is a leading cause of global disease burden, and both experimental and population-based studies suggest that differences in DNA methylation may be associated with the condition.

Science and Practice suggests that while antidepressants and short-term psychodynamic therapy both help alleviate depression, ...

Since its discovery by Leão in 1944 (ref. 1), spreading depression has perplexed neurologists, neurosurgeons and neuroscientists alike. From the first description in rabbits to its detection in ...

Learn more about a clinical trial examining a potential new treatment for depression in adult patients. Managing symptoms of depression can feel overwhelming, but you are not alone. If you experience ...

A novel analysis of more than 375 published studies concluded that the association between chronic pain and rates of depression and anxiety is staggering. The study found that 40% of adults with ...

Even individuals whose symptoms do not yet meet the criteria for clinical depression benefit from therapeutic interventions. This conclusion comes from a new meta-study by researchers who analyzed ...

“That’s wonderful,” says Sandy. “But…I think your wearable must be broken. The data from it look very irregular for your sleep these past 2 weeks.” “Oh,” says Joe, “it’s not broken. Actually, now that ...

Researchers have found preliminary evidence that combining the hallucinogenic compound psilocybin with cognitive behavioral ...

A single dose of psychedelics significantly reduced symptoms in people with major depressive disorder, a new study found. The clinical trial was led by researchers at Imperial College London, where ...

Depression is one of the leading causes of disability worldwide, affecting around 322 million people, yet it remains a complex and poorly understood condition. About 15 percent of the global ...