Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers study the "conversations" between cells inside the body. The tools, called ...

Australian researchers have discovered a new way that epithelial cells, which form layers in organs like the skin and stomach, attach to one another, and how they perceive growth signals at these ...

Now, MIT engineers have found that this "intercellular" fluid plays a major role in how tissues respond when squeezed, pressed, or physically deformed. Their findings could help scientists understand ...

They showed that basal spot junctions not only helped cells adhere to one another but were important for regulating Hippo signalling. "Our discovery of basal spot junctions in epithelial tissues has ...

Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...

Cells in humans and all vertebrates are tightly packed together to form organs and glands — tissues essential for living, breathing and moving. The narrow spaces between cells represent natural weak ...

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...