Learn how small mutations in non-coding DNA can alter sex development in rodents.

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Remarkably, 98 percent of our DNA does not code for genes. Once considered “junk DNA,” it is now well appreciated that these ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked ...

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Typically, female mouse embryos with two X chromosomes develop ovaries because a gene called Sox9 is suppressed. In male ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...