Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

This will be a conference call of the international commission developing a framework for considering technical, scientific, medical, regulatory, and ethical requirements for germline genome editing ( ...

Picture CRISPR-Cas9, a gene editing technology, as a GPS-guided scalpel: gRNA directs the Cas9 enzyme, a protein that cuts ...

An international group of scientists is calling for a moratorium on making inheritable changes to the human genome, specifically the use of the Crisper-Cas9 technique on DNA. The group met in ...

Scientists first read the human genome, a three-billion-letter biological book, in April 2003. Since then, researchers have steadily advanced the ability to write DNA, moving far beyond single-gene ...

The Case Western Reserve University Science and Human Rights Coalition will host Andrea Waksmunski, a PhD candidate in the Department of Genetics and Genome Sciences, for a talk titled “Ethics of ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Waking up this morning to news of the much-deserved Nobel Prize win for Emmanuelle Charpentier and Jennifer A. Doudna "for the development of a method for genome editing" confirms the importance of ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...