Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...
In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...
Flow cytometry enables researchers to label proteins of interest using fluorophore-conjugated antibodies and other fluorochromes. Much like immunohistochemistry, which produces two- or ...
For the first time, scientists have successfully created a type of mouse with a 100% functional human immune system and human-like gut microbiome. This 'humanized' mouse takes the guesswork out of ...
Humanized immune system (HIS) mice are invaluable for advancing preclinical research, with various models available to support lymphoid, myeloid and/or specific cell populations. T and NK cells are ...
Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic ...
Desmoplastic nodular medulloblastoma: A National Cancer Database analysis of patient demographics and survival. A phase 1 study to evaluate the safety and tolerability of BXQ-350, a novel sphingolipid ...
A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...
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