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Targeting microRNA communication reverses pancreatic cancer's immune suppression
In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer ...
(Nanowerk Spotlight) Cancer treatments have traditionally involved a difficult balance between effectiveness and side effects. For skin cancers, this challenge is particularly pronounced. Researchers ...
The Apollo longitudinal study enrolled patients with advanced NSCLC receiving ICI in first or subsequent lines. Plasma samples were collected at baseline and follow-up to prospectively assess miRNA ...
Glioblastoma (GBM) is the most common and highly aggressive primary brain tumor in adults. MicroRNAs (miRNAs) are pleiotropic post-transcriptional regulators of oncogenic pathways, and frequently lose ...
MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene ...
Small RNA was isolated from circulating tumor exosomes using mirVana isolation kit (Ambion, Austin, TX), and this low-molecular-weight RNA–enriched fraction was used for miRNA profiling as defined by ...
Researchers have shown that a novel delivery strategy can efficiently introduce a functional microRNA that has anti-cancer and angiogenic activities into two different types of cells--breast cancer ...
This study validated PROSTOX as predicting radiotherapy-induced genitourinary toxicity, which can be differentiated into acute and chronic with mirSNP-based signatures, in patients with prostate ...
The vector consists of a polyethylene glycolylated liposomal outer coat (providing immune evasion and prolonged circulation), a spindle-shaped nanomotor (resembling a flagellum, facilitating targeted ...
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