Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

Hepatic cell carcinoma (HCC), the fifth most prevalent malignancy worldwide and the fourth leading cause of cancer-related mortality, poses significant therapeutic challenges. Despite advancements in ...

Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This condition can cause symptoms including muscle weakness, ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...