Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to function properly. Tissue patterning is ...

Drosophila wing development is a paradigm for understanding how spatial information is conveyed by morphogen gradients to coordinate pattern formation and organ growth. Central to this process is ...

COLD SPRING HARBOR, N.Y. (May 6, 2010)-- Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-β, and various growth factors, is essential during embryogenesis. The establishment of ...

Tissue patterning is an important process during embryo formation, as well in adult tissue, which ensures that groups of cells are correctly arranged to allow them to function properly. Many studies ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 51 (Dec. 22, 2009), pp. 21707-21712 (6 pages) The dorsoventral (DV) patterning of the Drosophila embryo ...

The research team has shown that a transcriptional co-activator ANGUSTIFOLIA3 (AN3) forms a signaling gradient along the leaf proximal-to-distal axis to determine cell-proliferation domain. In an ...

Cells producing noise in the Wnt morphogen gradient are sensed by neighboring cells through E-cadherin and then eliminated through the Smad-ROS (reactive oxygen species) axis. Disclaimer: AAAS and ...

Researchers at Harvard Medical School and the Institute of Science and Technology (IST) Austria have discovered a key control mechanism that cells use to self-organize during early embryonic ...

In a recent study published in Nature Communications, researchers examinea the effects of temporal morphogen gradient during neural induction (NI) on the formation of brain organoids. Study: Temporal ...

Human neural organoids, derived from pluripotent stem cells, enable the study of the highly regulated process of human brain development in vitro. In vivo, the process is shaped by strict time- and ...