The most autofluorescent human muscle reserve cells are those that strongly express the transcription factor Pax7, an indicator of a state of deep quiescence. It is precisely these most "dormant" ...

In the study of 47 obese seniors with loss of muscle functionality, IMM01-STEM demonstrated clinically relevant improvements ...

Sarcopenia—reduced muscle mass, strength, and function—is often associated with aging and frequently impacts quality of life in the elderly. Individuals with sarcopenia are also prone to further ...

Working out doesn't just build muscle but, in later life, helps maintain a powerful cellular machine that repairs damaged ...

Stem cells that live in the muscle impart its ability to regenerate. After an injury, muscle stem cells activate and must expand in number to repair and make new muscle (marked by dystrophin in white) ...

Scientists at Duke-NUS Medical School have uncovered how exercise helps aging muscles regain their ability to repair ...

A common molecule found in the body could be targeted to turn aged muscle cells to become young again, helping prevent frailty in older people, a new study suggests. The populations of developed ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) describes the biology behind why muscle stem cells respond differently to aging or injury. The findings, ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...