Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring and impulse control, not drug-specific traits.

You’ve likely heard people mention that they have inherited certain health conditions from their family. These are known as genetic disorders—conditions passed down from parents through DNA. In this ...

At the genomic level, the researchers identified over 100 regions of the genome where genetic variants influence multiple disorders simultaneously. One region on chromosome 11 stood out as a "hotspot, ...

An immune-related gene has now been tied to a rare inherited neurological disorder, revealing an overlooked pathway in the nervous system.

The exact cause of personality disorders is unclear. However, genetics, neurological differences, and environmental factors may contribute to the development of these complex mental health conditions.

Despite modern high-throughput sequencing, the genetic cause of most rare movement disorders remains unclear. A research team in Bochum and Tübingen has now solved one piece of the puzzle: The ...

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators are trying to make the process more efficient using artificial intelligence. The team ...

Certain rare genetic disorders may cause a child to develop obesity. Health experts may refer to these conditions as syndromic childhood obesity. They may affect a child’s metabolism or cause them to ...

Each month, The Clinical Advisor makes one new clinical feature available ahead of print. Don’t forget to take the poll. The results will be published in the next month’s issue. Healthcare providers ...