ascopubs.org

Patterns of next-generation sequencing and associated next-line systemic therapy use in metastatic prostate cancer.

Recent treatment patterns in US-based real-world patients (pts) with metastatic hormone-sensitive prostate cancer (mHSPC). This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers ...
Labroots

Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read Sequencing

Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other genetic diseases. Almost all of these mosaic mutations begin as nucleotide mismatches or damage ...
Nature

Genomic, socio-environmental, and sequencing capability patterns in the surveillance of SARS-CoV-2 in Latin America and the Caribbean up to 2023

Latin America and the Caribbean (LAC) have been one of the most strongly impacted regions by the Coronavirus disease 2019 (COVID-19) emergency, with more than 83 million reported infections and 1.7 ...
Nature

Interpreting neural networks for biological sequences by learning stochastic masks

Sequence-based neural networks can learn to make accurate predictions from large biological datasets, but model interpretation remains challenging. Many existing feature attribution methods are ...
ascopubs.org

Real-world (rw) treatment (tx) patterns, sequencing, and outcomes in US patients (pts) with locally advanced or metastatic urothelial cancer (la/mUC) treated with avelumab ...

Utilization of neoadjuvant chemotherapy (NAC) and pathologic outcomes in upper tract urothelial carcinoma (UTUC). No visceral or thoracic lesions (n=86) 20.9 (19.7-NE) 10.6 (6.0-NE) 11.0 (8.2-20.4) ...