WHEN Stephanie Harding was first given a ‘wonder’ pain drug it seemed like the answer to her prayers. But almost a decade on, ...

HEALTH officials have issued an urgent addiction warning over three common pain and anxiety drugs. UK medicines watchdog the ...

Pregabalin was associated with an increased risk for heart failure relative to another widely used gabapentinoid, based on an observational study of Medicare records. Heart failure hospitalizations ...

In a recent study published in JAMA Network Open, researchers compared heart failure (HF) incidence between users of gabapentin and pregabalin. Non-opioid medications, such as gabapentin and ...

(Reuters Health) - A class of medications used for nerve and muscle pain, including the popular drug Lyrica, increases users' risks for suicidal behavior, unintentional overdoses, injuries and car ...

The antiseizure medication pregabalin, which is commonly prescribed for chronic pain, has been linked to an increased risk for heart failure (HF), particularly in those with a history of ...

Pregabalin 82.5mg, 165mg, 330mg; ext-rel tabs. Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.

Harry Sumnall receives and has received funding from grant awarding bodies for drug and alcohol research. He was an unpaid member of the Advisory Council on the Misuse of Drugs (ACMD) when the ...

Although pregabalin is mechanistically similar to gabapentin and shares similar advantages, such as a lack of pharmacokinetic interactions with other medications or enzyme induction, there are several ...

Retrospective cohort study compared heart failure risks of two nonopioid medications using Medicare data. The more potent pregabalin was associated with more heart failure events than gabapentin.