The cellular replicative DNA polymerases cannot initiate DNA synthesis without a priming 3′ OH. During DNA replication, this is supplied in the context of a short RNA primer molecule synthesized by ...
Structures of human primase reveal design of nucleotide elongation site and mode of Pol α tethering
Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 40 (October 1, 2013), pp. 15961-15966 (6 pages) Initiation of DNA synthesis in genomic duplication ...
In the early 1990s, Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry at Caltech, discovered an unexpected property of DNA--that it can act like an electrical wire to ...
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