Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk," may actually play powerful roles in regulating gene expression. Focusing ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...
Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.
Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...
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RNA splicing and processing genes emerge as central drivers of aging across tissues
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A ...
The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. The work was led by Ian Maze, a neuroepigeneticist ...
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