Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene ...

Structural variations (SVs)—large-scale changes in DNA sequence—play a crucial role in shaping traits such as yield, quality, and environmental adaptation in crops.

Whole-genome sequencing detects single nucleotide variants but tends to miss larger changes, such as deletions, insertions, duplications, and inversions. Using a new machine-learning method to analyze ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.