An important goal in drug development is to engineer inhibitors and ligands that have high binding affinities for their target molecules. In optimizing these interactions, the precise determination of ...

Each chemical reaction involves an enthalpy change that leads to a change in temperature. The amount of substance converted during the reaction determines the increase (i.e. exothermic reaction) or ...

Water impacts the quality of a wide range of products: chemicals, medicines, lithium-ion batteries, and food. Optimizing the water content present can help maintain product performance, shelf life and ...

Karl Fischer (KF) titration is a redox reaction which uses the consumption of water during the reaction to measure the amount of water in a sample. It is the reference method for water determination ...

Isothermal titration calorimetry (ITC) is a powerful and widely used method to measure the energetics of macromolecular interactions by recording a thermogram of differential heating power during a ...

Titration is an analytical chemistry technique used to find the concentration of an unknown solution, using a solution whose concentration is known. The latter is called the titrant and is usually ...

In this second edition of the “Guide to Phototitration” Mettler Toledo presents a detailed manual on photometric titration, authored by Kees Mooibroek, former Senior Application Chemist in the Market ...

The authors developed a robust, automated system to conduct Karl Fischer moisture assays for lyophilized products. Karl Fischer titration is one of the few assay techniques recognized by the US Food ...

Karl Fischer titration is a broadly used approach for calculating water content across multiple samples. However, to get accurate and reliable results, it’s essential to follow a proper workflow. Two ...