As people grow older, the same brain chemistry that once supported sharp thinking and stable mood can quietly start to work ...

Researchers show that the longevity protein SIRT6 controls how tryptophan is metabolized in the brain. Its loss shifts metabolism toward neurotoxic kynurenine pathways while reducing protective ...

Elevated tryptophan metabolism correlates with improved csDMARD response, reduced inflammation, and better clinical outcomes in rheumatoid arthritis patients. Multiomics analysis identified ...

"Our research positions the enzyme SIRT6 as a critical and primary drug target to combat degenerative brain pathology," Toiber said. "These findings change the way we understand the relationship ...

The connection between diet and mental wellness has gained increasing attention in recent years, with certain nutrients emerging as key players in brain health. Among these, tryptophan stands out as a ...

Medical researchers have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards ...

Microbiome dysbiosis—changes in the composition of gut microbes that alter the metabolites present—has long been implicated in playing a causative role in the pathophysiology of autism spectrum ...

Share on Pinterest Consuming tree nuts such as macadamia nuts may have cardiovascular benefits. Flavia Morlachetti/Getty Images A new study suggests that tree nuts may reduce certain risk factors for ...

In a recent study published in the journal Gut Microbes, a group of researchers examined how marital status and perceived emotional support relate to obesity-related outcomes and to coordinated ...

Scientists have uncovered how aging alters tryptophan metabolism in the brain, linking a longevity protein to ...