Morningstar

Single-Cell Multiomics Enables High-Resolution Vector Copy Number Profiling in CAR-T Therapies

Mission Bio, the leader in single-cell multiomics, published research in Molecular Therapy Advances showing that their Tapestri® platform can profile vector copy number (VCN), surface protein ...
Nature

Plasmid-normalized quantification of relative mitochondrial DNA copy number

Alterations of mitochondrial DNA (mtDNA) copy number have been associated with a wide variety of phenotypes and diseases. Unfortunately, the literature provides scarce methodical information about ...
The New England Journal of Medicine

Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy

The vector copy number in peripheral blood ranged from 0.10 to 1.55 at month 24 (assessed in 14 patients) and from 0.36 to 1.83 at month 36 (assessed in 3 patients) (Figure 1A); the number had ...
Nature

Episomal vectors based on S/MAR and the β-globin Replicator, encoding a synthetic transcriptional activator, mediate efficient γ-globin activation in haematopoietic cells

Episomes, in eukaryotes, are extrachromosomal, closed circular DNA molecules of a plasmid or a viral genome origin, that are replicated autonomously in the host cell and therefore, they bear ...
Yahoo Finance

Single-Cell Multiomics Enables High-Resolution Vector Copy Number Profiling in CAR-T Therapies

SOUTH SAN FRANCISCO, Calif., April 30, 2026--(BUSINESS WIRE)--Mission Bio, the leader in single-cell multiomics, published research in Molecular Therapy Advances showing that their Tapestri® platform ...