One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

Because mtDNA is only passed down along maternal lines and mutates at predictable rates, it has been used to help trace migration routes of early humans. In this activity, students will learn how ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

There are a total of 5 multi-subunit complexes in the inner membrane of the mitochondria, all of which are involved in the process of oxidative phosphorylation that precedes ATP production. Of these, ...

Understanding the relationship between mtDNA and animal growth could provide valuable information for selective breeding in aquaculture. However, the complex interactions between genetics and ...

When it comes to identification with DNA, forensic scientists have two basic approaches at their disposal. One approach analyzes nuclear DNA and is useful in identifying someone who is alive or has ...

Mitochondrial donation through pronuclear transfer resulted in several live births and reduced transmission of pathogenic mitochondrial DNA (mtDNA) variants, researchers reported. The study involved ...