Phase I Study of Adoptive T-Cell Therapy Using Antigen-Specific CD8+ T Cells for the Treatment of Patients With Metastatic Melanoma Two hundred fifty-one neuroblastoma specimens were analyzed using a ...

Inflammatory bowel disease (IBD) is a progressive, recurrent gastrointestinal disorder influenced by genetic, immunoregulatory and environmental factors and often requiring surgery for treatment.

Chromosome rearrangements are commonly associated with multiple disease states such as cancer and many developmental syndromes, including Down’s syndrome and autism spectrum disorders. The ...

Use of Agilent’s custom microarrays in the SOMAscan® assay will help drive biomarker discovery efforts as well as novel diagnostics and accelerated pharmaceutical development SANTA CLARA, Calif. & ...

An exhaustive algorithm for detecting copy number aberrations and large structural variants in whole-genome, mate-pair sequencing data. This is an ASCO Meeting Abstract from the 2014 ASCO Annual ...

A number of companies are using the lessons and technologies of traditional genomics--the microarray chief among them--to delve into the more challenging world of functional genomics and proteomics.

BETHESDA, Md. (July 22, 2004) -- Microarray technology, sometimes referred to as biochips, has been extensively used to investigate genome-wide expression patterns and has facilitated a revolution in ...

In releasing its DualChip microarray system, Eppendorf https://www.eppendorf.com of Hamburg, Germany, has blurred the lines between cDNA and oligonucleotide probes. The system makes use of Eppendorf's ...

Throughout his career, Luke Dannenberg, PhD, has held multiple positions in industry and academia that have put him in close proximity to oligonucleotide technologies. Trained as a scientist, he ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...