Imaging is a critical technique in biology—from identifying cancerous cells in biopsies to observing how immune cells like ...

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...

Machine learning is the ability of a machine to improve its performance based on previous results. Machine learning methods enable computers to learn without being explicitly programmed and have ...

Deciphering cellular microenvironments at atlas scale remains challenging. Here, authors present a scalable contrastive learning framework using cell-centric subgraphs to map niches across platforms.