Multidrug resistance (MDR) is a major cause of failure in cancer chemotherapy. It is commonly caused by efflux of anticancer drugs by ABC transporters including ABCG2. ABCG2 is also a cancer stem cell ...
Mild cognitive impairment (MCI) is characterized by a decline in cognitive functioning without significant interference in daily activities. Its high heterogeneity and elevated conversion rate to ...
Hirschsprung’s disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The ...
ABSTRACT: Objective: This study aimed to identify differentially expressed microRNAs (miRNAs) using microarray and to predict special target genes using bioinformatics methods in the neonatal rat ...
ABSTRACT: Objective: This study aimed to identify differentially expressed microRNAs (miRNAs) using microarray and to predict special target genes using bioinformatics methods in the neonatal rat ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Background: Type 2 diabetes mellitus (T2DM) has become a major global issue, with ...
Abstract: MicroRNAs (miRNAs) are reported to play essential roles in cancer initiation and progression and microarray technologies are intensively applied to study the miRNA expression profile in ...
Building on on the observation of an increase in miR-182-5p in diabetic patients, the authors investigated the role of miR-182-5p and its target gene LRP6 in dysregulated glucose tolerance and fatty ...