The Critical Role of Dystrophin in the Pathophysiology of Duchenne Muscular Dystrophy | NeurologyLive - Clinical Neurology News and Neurology Expert Insights
The Critical Role of Dystrophin in the Pathophysiology of Duchenne …
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Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
Sep 7, 2021
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Duchenne muscular dystrophy (DMD) is a devastating genetic condition that results in progressive muscle weakness, spinal deformities, heart failure and early mortality. While genetic therapies are being explored, current treatments only alleviate symptoms. However, MCW’s Dr. Brian Lin and his lab are researching a promising approach that examines a calcium channel which becomes hyperactive in DMD and how inhibiting that channel could counteract the leading cause of death in DMD patients. Learn m
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Duchenne muscular dystrophy (DMD) is a devastating genetic co…
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Duchenne muscular dystrophy is a progressive muscle wasting disease. It causes muscles to weaken over time because the body cannot produce dystrophin, a protein muscles need to stay strong. Duchenne affects every muscle in the body, including the heart and lungs. Despite the challenges, we choose faith, resilience, and joy. He has already surpassed what doctors once said was possible. Sharing our journey to spread Duchenne awareness and hope. If you’d like to support Duchenne awareness, drop a g
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Duchenne muscular dystrophy is a progressive muscle wasting disea…
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💡 What does “severe phenotype” mean in Duchenne muscular dystrophy (DMD)? When doctors talk about a phenotype, they’re referring to the way a condition shows up in someone’s body, the physical traits and symptoms that result from their genetics. In Duchenne, a severe phenotype usually means the condition progresses more quickly, often with earlier loss of abilities like walking, climbing stairs, or raising arms. This can also bring earlier complications with breathing, heart health, and other a
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💡 What does “severe phenotype” mean in Duchenne muscular dystr…
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