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alchetron.com
RNA induced silencing complex - Alchetron, the free social encyclopedia
The RNAinduced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which incorporates one strand of a singlestranded RNA (ssRNA) fragment, such as microRNA (miRNA), or doublestranded small interfering RNA (siRNA). The single strand acts as a template for RISC
3 months ago
Small interfering RNA SiRNA Therapy
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Cells use messenger RNA (mRNA) to carry instructions from DNA to make proteins. Sometimes, unwanted proteins can cause or contribute to disease. RNAi therapeutics disrupt this process by targeting specific mRNA molecules and preventing the production of disease-associated proteins. This video explains how RNAi therapeutics use small interfering RNA (siRNA) and a naturally occurring protein complex in the body to intercept and degrade target mRNA before harmful proteins can be made. Learn more ab
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2.4K views · 94 reactions | Higher circulating lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA molecule that reduces LP(a). New research findings are summarized in a short video. https://nej.md/3UK1KgE | The New England Journal of Medicine | Facebook
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